There is a need for vaccines against HSMI and CMS, as these diseases are causing losses and reduced welfare in Norwegian salmon farming today. Being able to culture virus in cells is the basic step for producing and studying a virus, and allows for testing and production of whole virus vaccines. We aim to develop and optimize culturing methods for PRV and PMCV, which have been difficult to propagate. We have already created a strong basis for this work by being able to culture PRV in fish primary cells.